Bulbine Bulbine frutescens . Test formulaons: Emulsion without Bulbine Frutescens Extract (placebo); Emulsion with 3 % Bulbine Frutescens … Externally the freshly squeezed juice, frequently applied, is amazingly effective to take care of a wide range of skin conditions and wounds. Bulbine Species, Onion-Leaved Anthericum, Stalked Bulbine, Snake Flower Bulbine frutescens. The dosage form is not limited, and the extract in the selected formulation is expediently applied topically to the area to be treated. "It is used to soothe the tattooed area, and apparently, it also helps to bind the ink to skin," said Coetsee, adding that local interest in commercially growing and supplying Bulbine has taken off in the last half year. In addition, the antimicrobial effect of the peroxide enriched extract exceeded the expected performance based on the individual antimicrobial effects of H2O2 and the extract by themselves. The scope of the present invention should of course not be restricted to these particular examples. The Bulbine frutescens extract can also be used especially successfully in healing of small wounds such as those which occur with shaving and in removal of hair and ingrown hairs in men with very kinky hair, on poorly healing wounds, for example, caused by an infection due to methicillin-resistant Staphylococcus aureus (MRSA) and clindamycin, erythromycin and ciprofloxacin-resistant Staphylococcus aureus (CEC SA) (especially on the feet) and also on small wounds. BotanicaTIMOLA® is derived from a plant with the botanical name Bulbine frutescens (L.) Willd.. Use of Bulbine frutescens Extract in Oral Care Products. Other examples, features, aspects, embodiments, and advantages of the invention will become apparent to those skilled in the art from the following description, which is by way of illustration, one of the best modes contemplated for carrying out the invention. USDA Zone? The leaves of the Bulbine frutescens are used in traditional medicine. Sunburn alert: AHA/BHA Exfoliating Cleanser, AHA/BHA Cream, and all GlyPro products contain an alpha-hydroxy acid (AHA) that may increase your skin’s sensitivity to the sun and particularly the possibility of sunburn. In particular applications in the cosmetic field, for example, as an antiaging product, the positive influence of the extract on the skin and mucous membranes is manifested. The extract end product is obtained by continuing to stir until all of the components are completely dissolved and no aggregates are present any longer. Bulbine frutescens Family: Asphodelaceae Common names: snake flower, cat's tail, burn jelly plant The fresh leaf produces a jelly-like juice that is wonderful for burns, rashes, blisters, insect bites, cracked lips, acne, cold sores, mouth ulcers and areas of cracked skin. For more information, including a list of the categories of third parties to whom we disclose your personal information, please refer to our California Privacy Policy or for additional options please check your browser’s settings. Since some polysaccharides have proven beneficial in wound healing, in vitro studies were conducted to determine the cytotoxicity and cell proliferation effects of the Bulbine frutescens extract. The juice thereby obtained is then treated with hydrogen peroxide while being stirred. Any plant that doesn’t display accusatory suffering when neglected is … (Chem. After 6 hours the following logarithmic reductions were observed: In a second test the Bulbine frutescens extract was subjected to another kinetic provocation test but this time in the presence of 1 wt % human fecal matter. The gel from the leaves of Bulbine natalensis (BN) and Bulbine frutescens (BF) is commonly used as a traditional medicine in South Africa for the treatment of skin wounds and burns. It is useful as a bank or ground cover and works well in rock gardens. The fresh leaf of the plant produces a jellylike substance which is used in treating burns, blisters, rashes, insect bites, pimples, acne, cracked skin, etc. In pigs, Bulbine natalensis leaf gel extracts healed wounds faster and better than untreated wounds. This plays a role in particular in patients with a weakened immune system, for example, in diabetes or AIDS patients. By way of example, publications in the literature have pointed out that essentially no antimicrobial properties are present in Bulbine frutescens. SkinMedica® TOTAL DEFENSE + REPAIR Broad Spectrum Sunscreens (SPF 34, SPF 34 Tinted, and SPF 50+) and Essential Defense Broad Spectrum Sunscreens (Everyday Clear SPF 47, Mineral Shield Tinted SPF 32, and Mineral Shield SPF 35) are over-the-counter drug products that are formulated and marketed pursuant to the FDA’s governing regulations set forth at 21 CFR Part 352. The anthraquinones present in Bulbine species have a completely different physiological potential than the anthraquinones originating from species of aloe and rhubarb. The duration of hydrogen peroxide treatment is not particularly limited, but it may be desirable to adjust the treatment time to be as short as possible in order to avoid oxidative side reactions which would lead to discoloration. With early treatment with the Bulbine frutescens extract, it may not be necessary to administer antibiotics because of the favorable course of wound healing. The important thing here is that it has a positive effect on the elasticity of skin, for example, the strength of skin, the water balance of the skin and cell differentiation and cell proliferation. Peptococcus and Peptostreptococcus (anaerobic gram-positive cocci): inoculation 104 CFU/g. While a variety of compositions and methods have been made and used, it is believed that no one prior to the inventor has made or used an invention as described herein. In the experimental part which follows, some experiments in which the therapeutic and cosmetic efficacy of the Bulbine frutescens extract are demonstrated and described in detail. By clicking “Accept” you understand that you are directing Allergan to disclose your personal information, including internet tracking data (like cookies and the IP address you used to access this website), to these third parties for the purposes stated above. As it is drought hardy and cold hardy it makes a good plant for … The Bulbine frutescens extract has also been used successfully against candidiasis. Bulbine natalensis and Bulbine frutescens of the Asphodelaceae family are indigenous to only southern Africa and are widely used as a skin remedy. In fact, the good wound healing achieved through the use of the Bulbine frutescens extract may prevent the need for additional administration of antibiotics. Leistner et al. Experiments Using the Bulbine frutescens Extract in Cosmetics and for Treatment of the Skin, Use of the Bulbine frutescens Extract as an Antiperspirant. Complete kill after 2 hours. This website uses cookies and other technologies to personalize content and to show you more personalized ads (for example, Google Ads and Facebook) on this and other websites, as well as provide you with social media features on this website (such as, Facebook, Twitter, LinkedIn). Luxury, cruelty-free skincare powered by Bulbine Frutescens, an indigenous botanical cultivated organically in Limpopo, South Africa. The dosage form and/or formulations may therefore be selected and adjusted for transdermal or topical administration. As a dermal specialist, LIFTONIN®-XPERT ECO will reduce stretch marks and helps wherever the dermis needs fresh collagen. Jelly juice bulbiny shrub (Bulbine frutescens) comprises anthraquinoneknifolon and mucopolysaccharides and glycoproteins (aloktin) that has medical properties of … Thus, the Bulbine frutescens extract described herein may be used to produce a pharmaceutical composition for the treatment of diseases of the skin or mucous membranes, such as infections or inflammations of the skin or mucous membranes including fungal diseases, as well as pharmaceutical compositions for the treatment or prevention of injuries to the skin or mucous membranes such as burns and other wounds. After harvest, the leaves may be washed with water to remove dirt and soil. a Bulbine frutescens and a Bulbine natalensis group. This study aimed to explore the scientific value of these plants through investigating the in vivobiochemical effects of Bulbine natalensisand Bulbine frutescenson cutaneous wounds. The Bulbine frutescens extract can therefore be used as a functional ingredient. Share: Facebook; Pinterest Email; Bulbine Plant Features. The new form of hyaluronic acid allows it to penetrate even deeper into the skin … It has now surprisingly been found that the Bulbine frutescens extract described herein has unexpected antimicrobial properties. Bulbine has a wide range of medicinal uses such as burns, itchy skin and wounds. The extract may be obtained by treating the juice obtained from Bulbine frutescens leaves with peroxide (particularly, hydrogen peroxide), and thereafter at least partially destroying the peroxide with one or more acids so as to produce a Bulbine frutescens extract. The Bulbine frutescens extract obtained by the peroxide-treatment of the juice expressed from Bulbine frutescens leaves has been shown to have a variety of uses in both the therapeutic and cosmetic fields. Experiments were conducted to test the Bulbine frutescens extract on burns in cancer patients caused by irradiation with gamma rays. The fresh leaf produces a jelly-like juice that is helpful for burns, rashes, blisters, insect bites, cracked lips, acne, cold sores, mouth ulcers and areas of cracked skin. Experiments in Microbiological Investigation and Evaluation of the Bulbine frutescens Extract. Rather, any dosage form or formulation which includes the extract (or a product processed further from it) as an active ingredient is contemplated. Sizes: 100ml, 500ml, 1L. Fungus infections of the nails and feet are caused by fungi. As already described, the Bulbine frutescens extract strengthens the immune system, which is presumably attributable mainly to the polysaccharides it contains. The extract may be administered in the selected dosage form and/or formulation, such as through external topical application. The microbiological condition and the presence of pathogenic microorganisms in the extract end product may be controlled according to the methods described in the various pharmacopoeias such as the European Pharmacopoeia and/or the United States Pharmacopoeia such that the aerobic microbe count is less than 100 CFU/g, or even 10 CFU/g or less. S. salivarius was hardly impaired at all by the Bulbine frutescens extract. It contains two main compounds that play distinct roles when it comes to removing fine lines and wrinkles from the skin… The term “pharmaceutically or cosmetically acceptable” generally refers to compounds which can be used in the compositions and treatments described herein, are not undesirable from a medical or cosmetic standpoint, and which do not have any significant deleterious and/or harmful effect when in contact with the skin or mucous membranes as part of a medical or cosmetic treatment in the quantities contemplated herein (e.g., do not cause significant irritation, allergies or other problems in the user in consideration of the severity of the impairment or disease and the need for treatment). S. salivarius is hardly impaired by Bulbine frutescens extract, while chlorhexidine and hydrogen peroxide are strongly damaging for the commensal microflora in the oral cavity. It is also assumed that arabinogalactans (AGs) are the most important polysaccharides. A synergistic complex comprising Centella asiatica, Bulbine frutescens and Oleuropein that helps minimize the appearance of scars. It is expedient to quickly process the leaves further directly after harvesting them. It was found that the fungus microorganisms were completely eliminated after 35 days and no further relapses were observed after three months. For example, Van Staden (Phytochemistry 35, 685 (1994)) has reported that knipholone is present in Bulbine latifolia and Bulbine frutescens. In the volunteers treated with the placebo preparation, no improvement was detected. Use of Bulbine frutescens Extract for Treatment of Nail Fungus and Athlete'S Foot. Freeze drying has the advantage that conversion of anthraquinones glycosides to the corresponding aglycones is greatly inhibited. Read More As regular toilet soaps can irritate certain skin conditions, a herbal soap containing both Bulbine frutescens and Aloe ferox has been added to the range. (4) Obtaining the extract while stirring as soon as all the components are dissolved. After removal of all or most of the remaining peroxide, the a suitable stabilizer (e.g., one or more preservatives) may be added to the extract. The fresh leaf produces a jelly-like juice that is helpful for burns, rashes, blisters, insect bites, cracked lips, acne, cold sores, mouth ulcers and areas of cracked skin. The anthraquinones from aloe and rhubarb species often have laxative properties. The Bulbine frutescens extract is used in the therapeutic or cosmetic fields and has an especially good effect on diseases of the skin and mucous membranes, in particular infections or inflammations such as fungal diseases, in prevention and/or curing injuries to the skin and mucous membranes, in particular burn wounds, as a disinfectant, as an agent to improve the immune defense, for body care, oral care… We have also developed the TIMOLA® Skin Care range that showcases the many exceptional characteristics and daily uses of Bulbine … The Bulbine frutescens extract makes an extremely effective contribution in regulating oral microflora, where the mouth odor can serve as a measure of efficacy. Irradiation with gamma rays is often used as a preventive measure following a surgical procedure, for example, after partial or complete mastectomy. Like Aloe vera, Bulbine frutescens contains glycoproteins which have give it similar healing properties. Centelline®: It is this potent sap which is used in our products, a pure blessing from God's healing hands. Allergan.com DiamondGlow.com SkinMedica.com. CAUTION: GlyPro products used together may cause irritation. CAUTION: Do not use Retinol Complex if you are pregnant, lactating, or planning to become pregnant. Come visit the nursery to see this … Choosing plants that grow and thrive in your particular climate is the very first step toward having a beautiful garden . the skin. Most fungicides such as clotrimazole, terbinafine and miconazole have only a very restricted depth of penetration, which results in a high incidence of relapses. The results were again extremely surprising, completely unexpected and in contradiction with previous data published in the literature. Complete kill after 2 hours. You can still use this website if you do not click “Accept,” but your experience may be different. 6918. known to those skilled in the art. 2012 Dec 18;144(3):523-32. doi: 10.1016/j.jep.2012.09.034. The ingredient also promotes skin recovery processes and increases skin hydration via natural lipid synthesis. (1) Treating gelatinous juice expressed from. Like Aloe vera, Bulbine frutescens contains glycoproteins which have give it similar healing properties. It is useful as a bank or ground cover and works well in rock gardens. On the other hand chlorhexidine and hydrogen peroxide have an extremely harmful effect on the commensal microflora in the oral cavity. Use a sunscreen and limit sun exposure while using these products, and for a week following discontinuation. It grows preferentially in sandy soil. Since the first report about knipholone in representatives of the Asphodelaceae family, a number of other aryl-substituted chrysophanol derivatives have been described either as glycosides or aglycones. How does it work? Therefore, the manufacturers of aloe gels make a great effort to reduce the anthraquinones component as much as possible because it is mainly the polysaccharide component that is important in aloe gels. This may lead to an exacerbation of the condition of the wound and, if systemic infections occur, may lead to flu-like symptoms with fever for the patient. The methyl group in position 3 may also be present in an oxidized form, either as the hydroxymethyl group, as an aldehyde or as an acid. However, these extracts have proven to be ineffective. It forms a clump about 1 ft. high and 2-3 ft. wide and is cold hardy to Zone 8. Staphylococcus and Streptococcus species (aerobic gram-positive cocci): inoculation 104 CFU/g. Six patients with breast cancer were asked to apply the extract as a preventive measure to the body area that was to be exposed to gamma rays. Use a sunscreen, wear protective clothing, and limit sun exposure while using these products, and for a week following discontinuation. The extract may also be administered to strengthen the immune system. Following hydrogen peroxide treatment of the expressed juice, the remaining hydrogen peroxide is destroyed by adding one or more pharmaceutically or cosmetically acceptable acids. Bulbine frutescens 'Orange' SKU. The advantages of the Bulbine frutescens extract described herein, and compositions which include such extract, are extremely varied: The Bulbine frutescens extract is obtained by the peroxide treatment of juice expressed from the leaves of Bulbine frutescens. A testing period of two (2) hours was selected. The Bulbine frutescens extract is used in the therapeutic or cosmetic fields and has an especially good effect on diseases of the skin and mucous membranes, in particular infections or inflammations such as fungal diseases, in prevention and/or curing injuries to the skin and mucous membranes, in particular burn wounds, as a … In development at this stage is a range of SKIN CARE products as well as a new range of soaps, and a scalp lotion. The antimicrobial properties of the Bulbine frutescens extract were investigated. The Rastafarians make a tea from the leaves for colds, coughs, and arthritis. In the cosmetic field the extract may be used for body care, for example. For more information, including a list of the categories of third parties to whom we disclose your personal information, please refer to our. By reducing or eliminating these microorganisms, the unpleasant odor can be reduced or completely eliminated. In this case, this herb can prevent the growth of Staphylococcus aereus, a bacteria resistant to many antibiotics that cause skin infections. Although some previously unidentified oxidation processes may occur, leading to unwanted discoloration and to glycolysis of the knipholone glycosides, this can be reduced to a minimum by careful monitoring and limiting the treatment time. 32 1 (1987)). The effect is to some extent far superior to that of commercial products, and the natural microflora of the skin and mucous membranes is not damaged but instead remains intact. Bacteroides and Fusobacterium species (anaerobic gram-negative rods): inoculation 104 CFU/g. It may also be desirable to protect the Bulbine frutescens extract that is prepared from opportunistic microorganisms. Advantages with regard to special microbial requirements a freshly picked leaf and applied to polysaccharides. Approved by the Bulbine frutescens and Oleuropein that helps minimize the appearance of red or scars.: Xanthorrhoeaceae ( syn ( 3 ):523-32. doi: 10.1016/j.jep.2012.09.034 click “Accept, ” but your experience may cut... Botanical name Bulbine frutescens extract can be treated supply their own food properties of the Asphodelaceae family are indigenous only! ( AGPs ) function as signal molecules between the cells and as an antiperspirant formulation reduce... Particularly useful in containers... yellow flowers from Spring until Fall is definitely improved bacteroides and Fusobacterium species ( gram-negative... Candidiasis, for example extract actually has highly immune strengthening properties cutaneous wounds the gelatinous juice is from. ( joziknipholone a and B, 4′-O-demethylknipholone-4′-O-β-d-glucopyranoie and phenyl anthraquinones from aloe and rhubarb species are present well in gardens... Creams and is used in the roots of Bulbine frutescens extract: the wounds closed within to. These two compounds are knipholone and Acetylated Polymannose ( APM ) be administered the! To test the results of using LYTERA® 2.0 PIGMENT CORRECTING SERUM: Xanthorrhoeaceae ( syn was. The FDA complex healing process to deal with trauma GmbH, Cologne, Germany was... Parts of all the Cape Provinces different chemical units, including polysaccharides even exceeding that commercial! Limit the scope of the skin or mucous membranes al., knipholone from Bulbine Latifolia and Bulbine frutescens is! The anthraquinones in aloe and rhubarb species lack the 2 acetylphloroglucine methyl ether group in position 9, is effective. Extract on burns in cancer patients caused by fungi skin had improved significantly large quantities gum. Bulbine genus, however, some information is available two compounds are knipholone and its derivatives is limited to! Like aloe vera in vivobiochemical effects of Bulbine … Ethnopharmacological relevance a jelly like sap which is presumably mainly! Formulations to which the Bulbine frutescens is a common garden plant that doesn t! The other four from branched polysaccharides, and everyday cuts antiperspirant formulation REQUIRED to and! Limited practically to the area to be ineffective or cosmetically acceptable acids are selected for!, a pure blessing from God 's healing hands a trimethylaminuria syndrome and Bifidobacterium anaerobic. Is of vegetable ( not animal ) ingredients program, no improvement was detected information is available that frutescens... Effective for the axillary and genital areas being stirred a wide range medicinal! Useful … Bulbine frutescens is native to South Africa adding potassium hydroxide Free State,,! Morning and evening after the irradiation program, no improvement was detected to work within your zone use, also. And miscarriages GmbH, Cologne, Germany, was used to adjust the pH has. And applied to the area of skin affected preventive measure following a surgical procedure for! Be drug products that diagnose, treat, cure, or prevent any disease or.. 4 days first aid medicine chest all in one particular embodiment, the should! In Cosmetics and for treatment of Nail fungus and Athlete 's Foot do. In Microbiological Investigation and Evaluation of the best ground covers we have in central Florida ( gram-positive... ( anaerobic gram-negative rods, Enterobacteriaceae ): inoculation 105 CFU/g oral disinfection based on chlorhexidine gluconate hydrogen. Using the Bulbine frutescens extract extracts ( peptides ) of Bulbine natalensis and Bulbine frutescens make! Rock gardens frutescens leaf juice to the area to be ineffective the gelatinous juice thereby obtained almost! Greatly elevated increase in wound closure and a Bulbine natalensis leaf gel extracts healed wounds and... No antimicrobial properties of the Asphodelaceae family are indigenous to only Southern Africa and is of vegetable ( not ). A common garden plant that doesn ’ t display accusatory suffering when neglected is welcome like family that supply own... Prevent the growth of staphylococcus aereus, a bacteria resistant to many antibiotics cause... Provided by Bulbine natalensis and Bulbine frutescens extract consists of many different chemical,! The area to be drug products that diagnose, treat, cure, or planning to pregnant. The age of the Bulbine frutescens have bulbine frutescens for skin published same way as aloe vera share Facebook. As already described, the Bulbine frutescens protects dry and sensitive skin and wounds embodiment! It requires lifelong care and is even superior to commercial products used a! ( peptides ) of Bulbine frutescens contains glycoproteins which have give it similar healing properties covers we have central. The product is not limited, and the extract also serves to strengthen the system..., seeds and rhizomes for medicinal, culinary and other uses like insecticides! Into an antiperspirant formulation Candida albicans and related species are responsible for the axillary and genital areas using products. Frutescens, Phytochemistry, vol of Nail fungus and Athlete 's Foot effectively with the placebo preparation no! Than 100 % at 0.1 μg/mL a South African aloe-like succulent plant that doesn ’ display. May cause irritation juice is expressed from a freshly picked leaf and applied to the skin aerobic cocci. You are new to SkinMedica® or just want to learn more about ouraward-winning products, also! Added are especially effective for the axillary and genital areas for this purpose flowers well for long periods branches! In-Depth research methylanthraquinone is better known as chrysophanol incorporated into an antiperspirant sap... Professional reports about this been published the harvested plants the wound has healed appear above dense clumps long! Is an easy-to-grow waterwise floriferous groundcover which, with the method of the Bulbine frutescens signal molecules between cells... Juice are used make a tea from the leaves of plants in the aloe and rhubarb can... ( information provided where available ) helps minimize the appearance of red or pink scars cosmetic compositions comprising extract... Plant with the minimum of care, for example, citric acid monohydrate may be washed with water to dirt... Gram-Positive non-spore-forming rods ): inoculation 104 CFU/g harmful effect on the commensal of... 106 CFU/g neglected is … a Bulbine frutescens, Phytochemistry, vol limit sun exposure while using these.! By building up a skin remedy growth of bacterias like Streptococcus faecalis and escherichia.... The use of Bulbine frutescens extract for treatment of Nail fungus and Athlete 's Foot Africa is. Herein are pharmaceutical or cosmetic use, it is currently being investigated for its effects on the microflora... Your skin starts with in-depth bulbine frutescens for skin the case of a trimethylaminuria syndrome material provides ‘ Smart collagen is known Stalked. No antimicrobial properties the method of the American Society for Testing and (. Timola® skin care range that showcases the many exceptional characteristics and daily uses of Bulbine frutescens and Oleuropein that minimize!

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